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Viewed together, these nine trials demonstrate that olmesartan medoxomil is associated with double-digit reductions in DBP and SBP at both the recommended starting and maximal dosages.

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Pregnancy: Female patients of childbearing age should be told about the consequences of second and third trimester exposure to drugs that act on the renin-angiotensin system and they should be told also that these consequences do not appear to have resulted from intrauterine drug exposure that has been limited to the first trimester.

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In patients with drug-induced enteropathy, an upper endoscopy with small-bowel biopsy may reveal sprue-like histological features, ranging from a mild alteration characterized only by increased intraepithelial lymphocytes to a flat mucosa with total mucosal atrophy, complete loss of villi, enhanced epithelial apoptosis, and crypt hyperplasia.

Alfuzosin: May enhance the hypotensive effect of Blood Pressure Lowering Agents.

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Tell your doctor if you have these signs and symptoms: dry mouth, thirst, weakness, tiredness or sleepiness, restlessness, confusion, seizures, muscle pains or cramps, muscle tiredness, dizziness or fainting, having little or no urine output, fast heartbeat, or nausea and vomiting.

Systemic Lupus Erythematosus: Thiazides (a component in BENICAR HCT and TRIBENZOR) have been reported to cause exacerbation or activation of systemic lupus erythematosus.

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TRIBENZOR also contains a thiazide diuretic (water pill), which may cause allergic reactions and changes in body salts (such as sodium and potassium) and fluids.

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